IFNG and neoplasm: For example, although there are drugs that target IFN-γ/CXCL10 pathway70, there are other subpopulations of cells with different properties that lead to tumor survival; the inhibition of both OXPHOS and glycolysis simultaneously in MCF7 and MDA-MB-231 cells with tamoxifen and glycolysis inhibitors increases the induced cytotoxicity71.