TLR7 and infection: HBV production in infected PHH is inhibited by exposure to CM from PBMCs stimulated with TLR2/7, TLR7, TLR7/8 and TLR9 agonists. We examined the effect of CM from PBMCs stimulated with different agonists of TLR2/7, TLR7, TLR7/8 and TLR9 on HBeAg (Fig. 2A) and HBsAg (Supplementary Fig. S3) production from PHH infected with HBV from 3 to 9 days post-infection (DPI).