The connection of the other genes found in our study (being differentially methylated in ECT responder groups) is less clear, yet no less interesting: An intergenic polymorphism (rs75213074) near the WSC domain containing 1 (WSCD1) gene has been previously associated with migraine [75], a neurological disorder sharing several biological abnormalities with depression [76]. The gene discussed is WSCD1; the disease is major depressive disorder.