IL1R2 and pachyonychia congenita: Multivariate logistics regression analysis indicated that PC (OR = 32.318, 95% CI 3.555, 293.782, p = 0.002) and IL1R2 expression (OR = 1.322 × 103, 95% CI 1.171 × 102, 1.494 × 104, p < 0.0001) were independent risk factors for ATRs (Table 2).