EGFR and AIDS dementia complex: In the current study, STAS was observed to be associated with wild-type EGFR. One possible explanation for the different frequencies of STAS based on different driver gene alterations could be that STAS is more frequently observed in poorly differentiated tumors including those with a solid/micropapillary pattern [25], and ALK or ROS1 rearrangements mainly exist in ADC with a predominant solid pattern [1, 26].