IGF1R and neoplasm: In 402 (26.8%) cases all tumor cells showed a weak (cCC-IGF1R 1+) immunostaining and in 4 (0.3%) cases 90% of all tumor cells within a given sample showed a strong cytoplasmic IGF1R expression (cCC-IGF1R 2+).The median HScore for cCC-IGF1R was 90 (range 0–190).