Interestingly, among the global glioma cases (Fig. 5b), the distribution range of the Pro/Pro genotype of p53 codon 72 was only 2.2–8.7% in the Caucasian population, excluding India and Brazil, whereas the distribution range of the Pro/Pro genotype of p53 codon 72 in India was close to that in our GBM data, in spite of Indians being affiliated with the Caucasian population. This evidence concerns the gene TP53 and central nervous system cancer.