ADORA2A and coronary artery disorder: Let us speculate that in the future, the level of exosomes in relation to the A2AR expression level, released by exocytosis into the extracellular space and representing a subtype of extracellular vesicles derived from endosomes, will be used to screen for CAD membrane particles or vesicles in a right-side-out or inside-out configuration, which could also be released in the blood during coronary artery disease.