PTEN and lymphoma: More recently, Baritaki and coworkers observed a similar response using the anti-CD20 mAb LFB-R603 in lymphoma cell lines: LFB-R603 inhibits both SNAIL and NF-κB and induces RKIP and PTEN, which in turn restores TRAIL-dependent apoptosis in TRAIL resistant non-Hodgin’s B-cell lymphoma [138].