We have previously shown that the ligands of human chemokine receptor CXCR2 (CXCL1, CXCl2, CXCL3, CXCL5, CXCL6, CXCL7 and CXCL8) were coregulated in breast cancers, presumably because of their common location in a narrow region of chromosome 4q [12,13]. The gene discussed is CXCR2; the disease is breast cancer.