In this study, we generated patient-specific iPSC lines from two young sporadic bvFTD patients using their peripheral blood mononuclear cells (PBMCs) and characterized their neurons (bvFTD-iPSNs) with respect to the expression level of FTD-tau, TDP-43, FUS, and activated caspase-3. Here, CASP3 is linked to frontotemporal dementia.