Hepatocellular carcinoma deletion gene 1 (DLC1), an antioncogene, is located on human chromosome 8p22 and is either expressed at low levels or not expressed in 50% of human hepatocellular carcinomas and many other human cancers (including colon cancer, lung cancer, prostate cancer and BC).11, 12, 13. The gene discussed is DLC1; the disease is breast cancer.