Suggested predictors include neutrophils and CD4 T cells [52], Serum Retinol-Binding Protein 4 [53], C-reactive protein [54] and 233 differential expressed genes in ALS monocytes, especially those related to inflammation (IL1B, IL8, FOSB, CXCL1, CXCL2) [55]. This evidence concerns the gene FOSB and amyotrophic lateral sclerosis.