Between timepoints 1 and 2, welders reported an increased prevalence of hypertension (welders: 26% at timepoint 1 to 41% at timepoint 2; controls: 15% at timepoint 1 and 26% at timepoint 2) and use of prescribed medication (beta blocker and angiotensin-converting enzyme – ACE – inhibitor) to treat hypertension (welders 12% at timepoint 1 to 21% at timepoint 2; controls: 4% at timepoint 1 and 7% at timepoint 2). The gene discussed is ACE; the disease is hypertensive disorder.