However, in contrast to the clinical use of PD‐L1 assessment in patients with melanoma and NSCLC,13, 14, 15 the clinical significance of PD‐L1 expression in GI cancer remains unclear from contradictory outcomes in multiple studies on the correlation between PD‐L1 expression and the ICI response or prognosis. Here, CD274 is linked to non-small cell lung carcinoma.