AKT1 and gastric cancer: The pathway enrichment of top 20 hub genes also shed light on the PI3K-AKT and MAPK signaling pathways, that is in line with investigations that phosphorylation by p38 MAPK results in the accumulation of ELAVL1 in the cytoplasm [33] and the elevation of ELAVL1 is essential for enhancing the proliferation of gastric cancer cells, which depends on the activation of PI3K-AKT and NF-κB signaling [34].