Similarly, the combination of crizotinib and IL10 was more effective in inhibiting tumor proliferation, invasion, and metastasis compared to crizotinib alone (the concentration of IL10 was 1 mg/ml, and crizotinib was 1 μM) (Figures 7(c) and 7(d); Figures 8(a) and 8(b)). This evidence concerns the gene IL10 and neoplasm.