The correlations between NEDD4L and the prognosis of melanoma were then verified by database of The Human Protein Atlas; as shown in Figure 4H-4I, in 20 cases of melanoma tissue, NEDD4L is moderately expressed in 2 cases, low in 10 cases, and undetected in 8 cases; moreover, the patients with high expression of NEDD4L in melanoma tissues showed better overall survival than those with low expression ones (Figure 4J). Here, NEDD4L is linked to melanoma.