Besides, by using immunofluorescence staining of cytokeratin 19 (CK-19), Hung et al. illustrated that in human cirrhotic livers and AAF- and CCL4-induced mouse livers, increased LC3-II was primarily located in cholangiocytes during DR, which was markedly attenuated by CQ inhibitor, suggesting that autophagy was positively correlated with DR in cirrhosis 40. This evidence concerns the gene KRT19 and Cirrhosis.