rs1295686 is intronic to IL13 and in strong LD (r2 > 0.98) with four other eSNPs, including a Gln144Arg missense SNP (rs20541) in IL13. At the CCL20 locus, the A allele of the cis-eQTL/reQTL (rs13034664) in PHA-stimulated T cells was associated with lower CCL20 expression as well as increased risk of childhood-onset asthma (Fig. 4a, Supplementary Fig. 8, Supplementary Data 4). The gene discussed is CCL20; the disease is childhood onset asthma.