When floating B-CLL cells were removed from the cultures, we observed that BDNF remained expressed (Fig. 2a, b) and secreted (Fig. 2d) by resting adherent cells in culture corresponding solely to NLC as detected by their respective markers CD14, CD68 and CD163 in culture (Fig. 1b). The gene discussed is CD14; the disease is B-cell chronic lymphocytic leukemia.