FOXM1, a transcription factor upstream of CYCLINB1 (a G2/M transition marker), has been reported to associate with cell proliferation, whose overexpression is related to metastasis and poor prognosis in ovarian [17] and clear cell renal carcinoma [18], which suggested high cellular cycling and cell proliferation in NSCLC patients with high recurrence risk score. The gene discussed is FOXM1; the disease is clear cell renal carcinoma.