This 7.3-year follow-up case-cohort analysis of 120,852 participants (58,279 men, and 62,573 women), and 733 CRC cases which were available for the molecular analysis, within the Netherlands Cohort Study on diet and cancer, reported that acrylamide intake was positively associated with risk of CRC, with activating KRAS mutations among men but not among women [25]. The gene discussed is KRAS; the disease is cancer.