FERMT1 has been reported to facilitate EMT by inducing the TGF signaling pathway in breast cancer, and NF-κB is an important signaling pathway through which TGF-β maintains the interstitial phenotype of tumor cells.27,28 Thus, we hypothesized that FERMT1 might promote EMT by inducing the NF-κB signaling pathway. The gene discussed is FERMT1; the disease is breast carcinoma.