Recently, a ceRNA network guided by lncRNAs has increasingly emerged as crucial molecular mechanism underlying carcinogenesis.33 Here, we revealed that miR‐342‐3p, an already identified tumour suppressor in HCC,34, 35 was sponged by ASMTL‐AS1 and its expression was negatively associated with ASMTL‐AS1 level in HCC tissues as well as residual tumours after insufficient RFA. The gene discussed is ASMTL; the disease is neoplasm.