VLDLR and hepatocellular carcinoma: For example, lncRNA FAL1 transferred by exosomes can increase HCC cell proliferation and migration.18 Linc‐VLDLR within exosomes regulates the response of HCC cells to chemotherapy.19 Exosomal microRNA‐103 derived from HCC cells promotes metastasis through modulating targeting junction proteins.20 However, whether exosomes also participate in the development and metastasis of residual HCC after insufficient RFA remains largely unknown.