Heterozygous p.Arg8Phefs*14 deletion in COL1A2 leading to nonsense mediated decay was recently identified in a Finnish family with primary osteoporosis.(32) Three affected individuals carried the mutation and presented nearly identical spinal fractures in radiographs, but they lacked otherwise typical features for both OI and EDS, such as blue sclerae, dentinogenesis imperfecta, hypermobility, muscle weakness, deformities, and short stature. The gene discussed is COL1A2; the disease is Ehlers-Danlos syndrome.