We observed a significant increase in AT1aR transcription in cardiac tissues of tumor-bearing vehicle-treated mice (3.14 ± 1.7 fold change compared to tumor-free vehicle-treated mice, p < 0.01) (Fig 5C), as well as for AT1bR (13.86 ± 7.2 fold change, p < 0.0001) (Fig 5C). This evidence concerns the gene AGTR1 and neoplasm.