EIF4E and myocardial infarction: Another study reported that canonical translation initiation is strongly inhibited following myocardial infarction, through a mechanism involving sequestration of eIF4E by 4E-BP1, although several other forms of regulation, including inhibition of Rheb/mTORC1 signaling were also observed, suggesting several paths are involved to 4E-BP control [204,205,206].