IDUA and Krabbe disease: For example, chloramphenicol has been shown to enhance alpha-L-iduronidase (IDUA) activity in cell lines of MPS I patients [73], whereas ataluren has shown effects on the galactocerebrosidase activity in Krabbe disease (KB) mice [74] and on palmitoyl-protein thioesterase 1 activity in NCL mice [75].