The observation that thymectomized animals have similar numbers of 2W1S-specific CD4+ T cells as sham surgical control mice at the time point coinciding with the start of Salmonella infection indicates that the elevated 2W1S-specific CD4+ T cells in thymectomized animals is in response to Salmonella infection, not thymectomy alone. This evidence concerns the gene CD4 and Salmonella Infections.