Aging-related tau astrogliopathy (ARTAG) is recently introduced terminology to describe age-related tauopathy changes within astroglial cells that are distinct from the glial tau pathology seen in well-characterised neurodegenerative diseases such as Pick’s disease (PiD), corticobasal degeneration (CBD), progressive supranuclear palsy (PSP), argyrophilic grain disease (AGD) and globular glial tauopathy (GGT) [15,16,17,18]. This evidence concerns the gene MAPT and argyrophilic grain disease.