Another NGS-based study of tumor samples from 195 patients (78% iCCA and 22% eCCA) reported similar heterogeneity, with a preponderance of IDH1 (30%), ARID1A (23%), BAP1 (20%), TP53 (20%), and FGFR2 gene fusions (14%) in iCCA [25]. This evidence concerns the gene TP53 and neoplasm.