The main Hippo components are differentially expressed across cancer types, such as in the cases of MST1/2 in soft tissue sarcomas [38,39,40], LATS1/2 in astrocytoma and breast cancers [41,42], TAZ in breast cancer [43,44], and MOB1 in lung and colon cancers [45,46]. This evidence concerns the gene LATS1 and breast cancer.