There were no significant differences between patients with A1298C MTHFR mutation vs. without mutation regarding gender (p = 0.318), the presence of carotid atheromatosis (p = 0.886), CAD (p = 0.459), PAD (p = 0.059) and T2DM (p = 0.618). The gene discussed is MTHFR; the disease is coronary artery disorder.