In a library of more than 35 close structural analogues, one compound 5‐fluoro‐2‐(3,4‐dimethoxyphenyl) benzothiazole (GW 610), showed outstanding potent and selective anticancer activity against, eg, colorectal and breast carcinoma models.15 GW 610 is a potent aryl hydrocarbon receptor (AhR) ligand, bioactivated via cytochrome P450 (CYP) 1A1 and 2W1 catalysis to electrophilic species that generate lethal DNA adducts in sensitive cancer cells.20, 21, 22. The gene discussed is AHR; the disease is cancer.