The frequency of IL-6 -597G/A genotypes significantly deviated from the HWE for GG, GA, AA [8 (20%), 29 (72.5%), 1 (2.5%) (observed) vs. 13.68, 17.64, 5.68 (predicted) (P≤0.001)] in HCV-positive HD patients. Here, IL6 is linked to Huntington disease.