Accordingly, REST has been suggested to play a central role in sustaining the tumorigenic potential of medulloblastoma cells due to its ability to block the differentiation of neuronal stem cells which promotes the self‐renewal capacity of tumor cells (Jørgensen et al., 2009; Majumader, 2006; Negrini, Prada, D’Alessandro, & Meldolesi, 2013). This evidence concerns the gene REST and neoplasm.