SHH and medulloblastoma: These include; the WNT subgroup, comprising 10% of cases and characterized by the activation of the wingless‐type signalling pathway (Jones et al., 2012); the sonic hedgehog (SHH) subgroup, which represents 20% of medulloblastomas and displays an activated SHH signalling pathway (Pugh et al., 2012); ‘Group 3’ which represents around 19% of cases and occurs exclusively in children, and ‘Group 4’ which makes up to 40% of cases and often exhibits isochromosome 17 amplification (Hovestadt et al., 2019).