The multivariate logistic regression analysis showed that female sex [OR, 1.76 (1.18–2.63); P = 0.005], hypertension [OR, 2.54 (1.67–3.86); P < 0.001], CAD [OR, 0.27 (0.16–0.46); P < 0.001], stroke family history [OR, 1.94 (1.26–2.97); P = 0.003], and hs-CRP level [OR, 0.21 (0.05–0.89); P = 0.034] were independently related to aneurysms (Table 2). The gene discussed is CRP; the disease is aneurysm.