In addition to these chemokine receptors, chemokine ligands such as CXCL1, CXCL2, CXCL5, CXCL6, CXCL8, and CXCL9 have been also significantly correlated with poor survival and metastasis in several cancers by recruiting MDSCs and suppressing the antitumoral activity of CD8+ T effectors cells. This evidence concerns the gene CXCL8 and cancer.