Although several lncRNAs, including HILNC25, lncRNA MEG3, and MALAT-1, have been found to contribute to diabetes (Arnes et al., 2016; Lu et al., 2016; You et al., 2016), little is known about the expression profiles of lncRNAs in T1DM patients and whether lncRNAs can be used as diagnostic or prognostic tool for T1DM. This evidence concerns the gene MEG3 and diabetes mellitus.