TNF and COVID-19: Various studies have suggested the occurrence of cytokine storm in critically ill COVID-19 patients due to higher plasma circulating cytokine levels (interleukin [IL]-2, IL-7, IL-10, interferon-inducing protein-10 [IP-10], granulocyte-colony stimulating factor [GSCF], macrophage inflammatory protein-1a [MIP1a], monocyte chemoattractant protein 1 [MCP1], and tumor necrosis factor alpha [TNF-α]) in severe cases (2).