Apart from TIPRL expression, tumor TNM stage (P = 0.000 and P = 0.000, respectively), depth of invasion (P = 0.001 and P = 0.006, respectively), lymph node metastasis (P = 0.000 and P = 0.002, respectively), distant metastasis (P = 0.000 and P = 0.000, respectively), and tumor histological differentiation (P = 0.017 and P = 0.004, respectively) were also significant predictors of outcome. This evidence concerns the gene TIPRL and neoplasm.