TIPRL and cancer: Based on a literature review of the candidate miRNAs' function, TargetScan (http://www.targetscan.org/) and microRNA.org (http://www.microrna.org/) analysis revealed that the TIPRL 3′-untranslated region (3′-UTR) contained cancer-related miRNAs-binding sites, including miR-216a-5p, miR-383-5p, miR-29a-3p, miR-29b-3p, miR-29c-3p, miR-101-3p, miR-124-3p, miR-128-3p, miR-224-5p, miR-433-3p, miR-450a-5p, miR-506-3p, and miR-873-5p (Figure 3A).