Functional enrichment analysis of myometrial DEGs in our study identified SCN4B associated with “muscle contraction” and was also significantly correlated with expression of the m6A regulator “cluster.” Moreover, expression of SCN4B mRNA was decreased in myometrium of adenomyosis patients, as were METTL3 and FTO. Thus, m6A RNA methylation regulators may regulate cell adhesion through SCN4B, further contributing to adenomyosis development. This evidence concerns the gene METTL3 and adenomyosis.