FOXP1 and juvenile Huntington disease: Braccioli et al. (2017) reported that FOXP1 can adjust neural stem cells (NSCs) neurogenesis via Notch signaling and foster the differentiation of embryonic NSCs to neurons and astrocytes in vitro. Li et al. (2015) demonstrated that FOXP1 has vital influences on modulating neuronal migration and morphogenesis in cortical regions. FOXP1 mutations reportedly contribute to nervous system disorders including Huntington disease (Tang et al., 2012), autism (O’Roak et al., 2011; Chien et al., 2013), and epilepsy (Jay et al., 2019).