For instance, a recent clinical trial that accounts for both viral pathogenesis and immunopathology, by administrating triple-therapy consisting of IFN-1β, lopinavir-ritonavir and ribavirin, alleviated symptoms, suppressed IL-6 levels and shortened duration of viral-shedding and hospital stay in mild-to-moderate COVID-19 patients (9). This evidence concerns the gene IL6 and COVID-19.