TREM2 and Alzheimer disease: Importantly, other TREM2 variants have also been studied for their association with the risk of AD, including R62H (Huang et al., 2004; Guerreiro et al., 2013; Jonsson et al., 2013; Jin S.C. et al., 2014; Roussos et al., 2015; Ghani et al., 2016; Song et al., 2017; Sims et al., 2017).