Furthermore, ex vivo analysis of dissected tumour samples revealed that the expression of E-Cadherin and GnT-III, in addition with the phosphorylation of JNK and c-Jun was enhanced, while the phosphorylation of AKT and GSK-3β and the expression of N-Cadherin and Snail were reduced (Fig. 6c–j, Supplementary Fig. 7C). This evidence concerns the gene AKT1 and neoplasm.