We found that several HRR-associated genes, including DDB2, RAD51, BRCA1, XRCC2 and BRCA2, are overexpressed in melanoma cells compared to primary melanocyte cultures, while the expression of the NER-associated genes XPA, ERCC1 and ERCC4 showed no clear differences (Fig. 1a). The gene discussed is XPA; the disease is melanoma.