Now that miR-3622a-3p was demonstrated to regulate migration and invasion abilities of CRC cells in our study and SALL4 has been reported to induce EMT by Wnt/beta-catenin signaling pathway37,38, the effects of miR-3622a-3p on EMT and Wnt/beta-catenin signaling pathway were explored. Here, SALL4 is linked to colorectal carcinoma.