Note: ↑, increase; ↓, decrease; Acrp30, Adiponectin; AdipoR2, adiponectin receptor type 2; ALD, alcoholic liver disease; ALT, alanine aminotransferase; HCC, hepatocellular carcinoma; HMW, high molecular weight; IL, interleukin; LT, liver transplantation; MMW, middle molecular weight; NAFLD, nonalcoholic fatty liver disease; NASH, nonalcoholic steatohepatitis; TNF-α, tumor necrosis factor alpha. The gene discussed is GPT; the disease is metabolic dysfunction-associated steatotic liver disease.